Toprol-XL side effects

OK FOLKS -HERE'S A GOOD ONE FOR YA- Just over a year ago I was on a heart transplant list. Today my heart function is normal and I am off ALL HEART MEDS. Even after finding out my heart function level was normal I was still living a nightmare for some unexplained reason. After MONTHS of tests and everyone telling me I was nuts a neurologist finally found out I was having seizure activity. Funny how my "seizure activity" feels EXACTLY how I felt when they increased my beta blocker dosage. I'm telling all of you.. This beta blocker helps some but they are burying their mistakes. I now know all of my ER trips, only to have them laugh and have them send me back home, were do to seizures caused by beta blockers while I had heart failure. I'm lucky to be alive.... and now that my heart function is good I have to fight this seizure BS. *REMEMBER THIS - Only YOU know what your body is telling you.. LISTEN TO IT! But do be careful.. You can't just stop taking a beta blocker.. Good luck all cuz we sure need it!

Started Toprol XL 75 mg in December 2007. I had been having gastrointestinal issues and after much searching, I decreased the Toprol to 50 mg. and the symptoms went away. Before I figured it out, I had difficulty having bowel movements and unirating.

I've booen on 100 mmg of toprol for over ten years. Have all the side effects including tinnitus and impotence. Last week for chest pain spent the night at the er , three blood tests, three ekgs, a stellar stress test and echo. All normal and still the sense of doom and the pain under the breastbone... This has been ruining my life. I'm furious after reading all this testimonies . Olease someone give me advise. ******

I'm a 30 yr old healthy male. I went to the ER, and then the Dr., about 4 weeks ago after waking up with intense pain in the veins of my right arm and having pounding palps. I had just been told some extremely stressful news the night before, so I was pretty sure this was blood pressure & stress related. ... EKG showed Wolf-Parkinson-White syndrome, so that's what the Dr's assumed was the problem. I never knew what it was called, but I've had my heart race due to WPW many times since I was a young child .. this did not seem to be related. This was just pounding.

The cardiologist put me on 50mg of Toprol XL daily to control the WPW - even though that wasn't acting up. I left confused. Pharmacy issued generic Metoprolol Succinate mfg. by Sandoz.

I didn't want to be on meds, so I didn't take it for the first few days, hoping that I would return to normal. After all, I just woke up with this all of the sudden.. I had been fine the day before. Palps continued, though, so eventually I relented and started taking the meds.

The first two or three weeks were filled with ups and downs. Exhaustion, palpitations and anxiety would come and go.

This past weekend things got really bad. I began having anxiety attacks -- I think that's what it was, I'd never had one before -- and my vision was totally screwed up. I couldn't focus on anything and was sensitive to some lighting. Black text on a bright white screen (lcd monitor) was especially hard to read. I was completely in a dazed & confused state. Loud noises and crowds were bothering me... which was awful, considering it was my best friend's wedding. Also had headaches, lightheadedness & loss of appetite. These side effects came and went on Friday & Saturday and were pretty constant on Sunday & Monday.

I decided to quit Toprol cold-turkey on Sunday. I have been 2 days without. I have used L-Theamine to reduce stress and keep my blood pressure steady. It seems to be working. I also began taking CoQ10 today after reading some good things about it here.

My vision & mental focus is beginning to improve after 3 days of disabilitating problems. Anxiety has also improved. I even attempted to "get back to normal" at work today, but had to leave after only an hour of strenuous exercise in the heat. Vision problems returned, anxiety set in. It's like riding a really freaking scary roller coaster, except with a legitimate fear that this thing might kill you.

I will update this as time goes by, to let you all know how things worked out for me. I'm really hoping to be mostly back to normal in another day or two, since I haven't been on for very long. Hopefully this will be of help to someone in the future. Damn, I Wish I had never gotten on this stuff.

I started taking Toprol 4 months after having my baby. I never had High Blood Pressure until I was 2 months pregnant and It continued throughout my pregnancy. Four months after giving birth my BP kept creeping up so I went to my doctor and she prescribed 25mg of Toprol. I have been taking Toprol for a year and a half, I have gained over 20 pounds, I have felt like I have been walking in a fog, loss of concentration, been diagnosed with depression, I have slept at night but not feeling rested. I went off the meds for an allergy test and immediately realized that I was sleeping better and feeling rested, so I was monitoring my BP and It has been okay so I have stayed off the meds. I never realized that my problems could have been linked to this med until I went off the Toprol. My question is how long before the weight will come off. I was working out 5 days a week and watching what I ate for over 2 months while on the Toprol and no change. I am hoping that since I am off of Toprol I will start dropping a few pounds soon.

Hello everyone,
OOPS, I put the wrong date in my post. PLEASE READ MY POST FROM JUNE 19TH NOT THE 18TH.
:-)
Joyce47oh :-)

I decided a long time ago, Doctor's are not the best listeners!! I am a nurse, I know!! Read my post today June 18th. I have been praying for an answer to all my symptoms, especially the profuse sweating I have been having for the past year!!! I believe I have found my answer at this site. Thank God I found it. All because I was looking up info about Toprol because after the doctor increased my dosage yesterday , today my ankles and feet swelled up like balloons!!!!! Now I have pitting edema!!!
I have gone to a # of doctor's in the past year and a half and I think they believe it is all " in my head"!!! I have been so depressed. My husband has even threatened to leave me. NO interest in much of anything. I don't know what it is like to sleep anymore :-( My husband says " just close your eyes and sleep like a normal person". Maybe after he reads the posts at this site he will begin to understand that everything I have been going through is "REAL". I am calling my Dr. in the morning and she will WEAN me off this awful drug!!! My BP has been going up since I have been on Toprol instead of going down. I have wondered why the Dr. didn't just change the med. It really makes one wonder. DO the Dr's ever hear what we are saying???? I would be happy to share stories with anyone on this site. How many of you have experienced profuse sweating???? The doctor will WEAN me off this drug!!! :-)
God bless everyone!! I pray you all get off this drug!! It needs to be pulled by the FDA!!!
Joyce47oh ;-)

WOW, I am so happy to find this site. I am a 56 yr old female. I too am on Toprol. I was on 75 mg 2 x's a day for HPB and mitral valve prolapse pain. Then yesterday the Dr. increased my dose to 100 mg 2x's a day .Today my ankles and feet blew up like balloons. I have been having profuse sweating and was cold and clammy for the past year and no Dr could tell me why!! NO sex drive , depression,sleep apnea, severe insomnia, brain fog, short term memory issues, moody, irritable, my husband has threatened to leave me. NO appetite!! Floaters in my eyes started a few months ago, I have so many symptoms that I have read in all your posts. No quality of life for the past year. I have felt like I was losing my mind, gained 35 lbs in past 2 years without changing my eating habits. I gained the weight after I had lost 50 lbs. Been on Toprol about 2 1/2 years ( I think ) Every symptom I have experienced I have read in your posts!! I have type 2 diabetes and am on glucophage, I also take 10 other scripts. I have fibromyalgia and chronic fatigue, RSD in my left arm, muscle pain and joint pain. Pain in my right upper qaudrant. Nausea/ some vomiting, NO ENERGY, Loss of interest in most of life. So now after reading all your posts I have to ask myself, are all my symptoms linked to the Toprol and not syndromes or illnesses? I am calling my doctor in the morning and getting off this med!! They will just have to put me on something else!!!
So how do I post to receive replies?
Joyce47oh

55 year old female
I have been on Toprol 5 years. 50mg. it works for me but since it went generic,I wonder...I am on 10mg lexapro and December started the vivelle-dot for my hotflashes. It is now June and the last 4 weeks my hair is falling out big time.
It is so thin I have to wear a scarf as not to scare small children at work.!! :)
I have talked to a couple of hairdressers and they have told me many of they're clients with thinning hair were on Toprol.
Anyone heard of this? Please help me figure this out.

I was on it for 6 months and the Dr. decided to change my medications. Toprol wasn't keeping my blood pressure down. I had bad chest pains and severe sweating so after 2 weeks he put me back on the Toprol. Bad mistake every time I took the Toprol My heart felt like it was skipping a beat and I would black out. Now I can't take it either. I'm on lisinopril now. Which is fine, it's keeping my blood pressure down. But still felt like my heart is skipping beats, ended up in the E.R.
they did pick up the skipped beats on an ecg and decided it was prob because the toprol is still in my system. My heart feels like it is racing all the time, and I'm having anxiety and shaking. I wish this stuff would get out of my system. good luck to everyone.
sabrina

My mother is on Toprol-XL, and she has complained of being so fatigued, she sleeps so much, and this is someone who has always had a tremendous amount of energy. The other thing, and I would love a reply to this - she said she's experienced something at night while sleeping that feels like a seizure. She describes this as follows, "like my brain is shaking or trembling inside my head and my hands are trembling too." Has anyone else experienced this? Please let me know.

I have taken toprol for seven years. I never had any bad side effects and it controlled my blood pressure most of the time. However, I suffer from anxiety and depression and was recently put on Lexapro. My heart rate dropped into the 40's and I was exhausted all the time. Turns out Lexapro interacts with Toprol in that the drug (Toprol) does not break down in your system and keeps building up! Because the Lexapro was helping my anxiety I decided to lower the Toprol dosage. Down to 12.5 mg and still extremely low heart rate and fatigue. Decided to go off the Toprol and monitor my blood pressure, which has been amazingly good so far. Went off completely six days ago and it has been rough. Anxiety, insomnia, pounding heart, heart palpitations. This stuff is a real B*tch to get off from. Have talked to both the pharmacist and my doctor and both said to NOT start taking it again. There are plenty of newer medications out there. I also experienced weight gain when I first started taking it...I think because it slows your metabolism down. So now I am on xanax to counteract the Toprol until the Lexapro kicks in more. It it isn't one thing, it's another.

WEIGHT GAIN, NUMBNESS IN FINGERS AND FEET. LET PAIN. I ALREADY HAVE RHEUMATOID ARTHRITIS, MIXED CONNECTIVE TISSUE DISEASE, THYROID DISEASE AND AM MISERABLE ON THIS.

I GAINED 12 POUNDS IN TWO MONTHS. I'M IN A FOG AND CAN'T REMEMBER ANYTHING. HAVE REALLY BAD LEG PAIN TRYING TO EXERCISE.

I THINK THIS DRUG SLOWED MY METABOLISM.

I started to use toprol the generic type 3 weeks ago, I have the worst panic attacks, anxiety and depression ever, I never had depression in my life before, this medication took my pleasure of life away from me. I am getting off this horrible medication, started with 50, now I am on 25 (symptoms better), in two days I will be down to 12.5, then seven and is bye, bye. I read is not good to go cold turkey on this medication.

I am 36 and take 100 mg of generic Toprol a day. I was put on it due to many ( I mean 30 to 40) palps a day. I had been on Atenolol for about 5 years and the doctors told me it had simply quit working. I had an echo and a 24 hour holtor monitor and both came back negative, yet I felt like I was dying daily. My palps have diminished with the medicine, with a change in diet and running 5 or 6 days a week for about 3 miles. Caffeine and alcholol have almost been excluded. I do have cold hands and feet and have had much trouble losing weight. Stomach cramps and an upper right side cramps have been an issue. After reading your posts I think we need to get off this stuff

My BP had been slightly elevated for over a year and my doctor felt it was time for medication. He started me on 25mgs and continued to increase it till I reached 100mgs. I started having anxiety attacks, lightheadedness, dizziness and finally ended up so sick that I was in bed for three days. It was the toprol. I was only on toprol for 3months but found out that trying to come off the drug was the hardest thing I have done. I never had BP spikes before but at the end of the first 24 hrs. without Toprol my BP was hitting 200/104. I went to ER. Matter of fact, the spikes continued and I was in and out of ER until I was finally admitted for tests. The spikes were also accompanied by flushing, rapid pulse(122 beats per minute), lightheadedness and diarrhea.Many times I thought I was having a heart attack. I have seen two cardiologists, an internist and now an endocrinologist for these "BP spikes". All tests come back normal. No matter what the new medication is, nor how low my BP might stay for up to three days....the episodes still happen. My BP can go from a normal range too 200 systolic in a matter of less than 1/2 hr..........Has anyone else had spikes in their BP when coming off toprol. It has been 11 months since stopping this awful drug and I still I no answers....but I have a pile of medical bills.

I started Metoprolol 6 months ago while in the ER. I was weak with a virus and every time I got up and did anything, my heart would race and would feel weaker. I have white coat syndrome so while I was in the ER my BP went up to 227/110. They gave me 25 mg of Toprol and a prescription for 12.5 mg a day. I have gained 17 lbs in 6 months, have zero energy, tired all the time, insomnia, and am depressed for the first time in my life,ad I know it has to be from the Metoprolol. I tried to quit it and 3 days later my heart was racing so bad and my blood pressure was real high. I want to try to quit it but am afraid to. Any suggestions on how to quit it?

I feel very shaky, especially when I get up in the mornings. I am always tired, even after sleeping in. I take toprol for my svt episodes which were becoming quite frequent - 2 or 3 per month. I also have high blood pressure and take another med for this (HZT).

I started taking the generic of Toprol (metaprolol) 3 months ago. I'm on 150mg per day for a rapid heartbeat, I'm 39 years old. It has helped my heart problems but I don't know if the side effects are worth it. I experience major fatigue that may last a week at a time and subside for a few days, aches in my back and neck (which I've learned may also be attributed to the Lipitor that I am also on), and my worse symptom is constant diarrhea. Some days I will run to the BR 15 times in one day. It seems to subside by dinner time, but that is probably because I stay away from food all afternoon. I'm fortunate that I am a stay at home mom I can't imagine having to go to work in this condition!

I have been on generic Toprol since 2005 to control my high blood pressure. I have many of the symptoms you all experience, tiredness, occasional dizziness, some weight gain. However, the most debilitating side effect I am suffering is neck flushing and anxiety attacks, my chest and neck turn bright red practically whenever people talk to me and I've never had this problem prior to taking this drug, I am shy but not that shy. Now I feel like I have to wear turtlenecks all the time or people will ask me what is wrong with you, are you allergic, etc... I can't even have a regular conversation with my co-workers without my neck turning red and breathing hard. It's ridiculous and I want to know if anyone else has this problem or if I'm just mental.

Thanks.

Hi all! I have recently started to have a very strange feeling and thought I would post here to see if anyone else can elaborate on it.

I switched from private healthcare to the VA system in March 2008 and the MD at the VA immediately switched me from Toprol XL 100mg per day to Norvasc ( Amlodipine Besylate) 5mg, a generic version and from Zetia 10mg to Zocor. This is mainly due to the fact that the VA does not have the Toprol XL or the Zetia in their pharmacy.

I am a very active person, work out 3 times per week, play tournament level racquetball and generally stay very active. I was feeling fine on this medication for almost 3 years with the only side effect being a little light-headed feeling with hard physical activity. Approximately 2-3 weeks after changing meds I started to get this lumpy feeling in my chest and then it started to progress into an air hunger feeling which felt like my breath was being taken away for a split second. I called the MD at the VA and requested to go back on metoprolol tartrate, which is what the VA has in place of the metoprolol succinate (Toprol XL). The air gasp feeling has only gotten worse and with any excertion I become tired now and start to get the gaspy feeling. Very scary. When it started to get real bad one evening I called 911 and went to the emergency room. Tests came back "ridiculously normal" the ER MD stated. Went back to the VA and the same MD, who doesn't listen, says I am under stress and prescribed me Paxil. I am completely lost as to what to do. I am going in to have another EKG and a holter monitor put on as well as a stress test.

Does anyone have any advice for me? I am desperate to get this resolved as fast as I can. Feel terrible lately and the MD doesn't seem to be listening to me.

Help!

I was put on Toprol xl after a visit to the Dr. because of a kidney stone. My pressure was extremely high at the time, probably more due to the fact that my kidney wasn't functioning properly with the stone. Anyway, 50 mg of the generic once a day. I was also given lipitor. I stopped the lipitor 2 months after taking it, because I felt like my body was put through a meat grinder....slowly. After 2 months on the Toprol, I have been extremely anxious, tired and my voice has suddenly become very weak. I even went to the ENT to make sure there was nothing else going on. Everything was fine. I cut the dose from 50 mg to 25 and within 2 days my voice returned to normal. The problem is my BP also went up. Anyone else have voice problems with this med?

Hi my history started from last couple months when I realize my bp went up very high(160/100) so I started metoprolol succinate 25mg,for couple days i felt fine and my bp went down but I noticed some pain in my right side so i thought maybe is the liver problem and i started to get off.After a week i was suffered from withdrawal(first week i decreased dose to 12,5mg)then my bp was very high so i called doctor and he prescribed metoprolol 100 mg and lisinopril 25(i never used this one)and hydloxiazyde 12,5 and i felt better for couple weeks then I started to get heart palpitation and very low bp so I quit hydroxiazyde and now I'm on toprol xl (oryginal brand) and still have chest tightness (i switch metoprolol to toprol one day ago)and how you guys divide the tablets to get exact amount its hard

I am experiencing cold intolerance that is embarrassing and also horrific. Impossible to get warm, even with an electric blanket. Anyone?

Hi,
I just found this site and was wondering how long it takes this horrible drug to leave your system. I have been taking it for a year and have suffered the WORST depression and anxiety attacks from it. I have been lucky enough to have never suffered from any of these symptoms in my entire life and my heart goes ou to those who live with it every day
So far I have lost my job, any chance of sleep, and I can barely get out of the house in the morning. Its having a direct affect on my marriage, I have lost all intest in my hobbies, unable to concentrate, I'm just a wreck. I just saw my Dr. last week and she made my dose smaller (25 MG) for the past week and I feel worse. Is there any ending to this?

I too had HORRIBLE experiences on Toprol-XL. I was put on it after I walked into a doctor's office and my BP was 235/152. Yep..you read that right! Scary times. I started taking the med, and I too gained 35 pounds with no change in diet. I was tired, weak, groggy - I honestly felt like I was slowly dying. At that point, I decided that high blood pressure was far better than the experience I had on Toprol. It ruined my marriage. Can you say ZERO libido? I decided that I would try a different form of metroprolol - metroprolol tartrate versus succinate. I did this when I went out of town - I honestly thought my heart was going to pound out of my chest - coming off this medication was horrible, and if the other posts are true about this being worse to come off than opiates, I REALLY feel for addicts now. I have been off the Toprol now for about 9 months, and I feel so much better. I've lost what I call the Toprol weight, and I made some life changes. I did the following: (A) I purchased a rebounder (mini-trampoline) and have built up from 5 minutes per day to 15 minutes per day (goal = 40 minutes per day) - there are HUGE health benefits in rebounding and it's really easy on my joints (google the benefits - I promise you won't be disappointed). I turn on the TV or turn on my Ipod and bounce away. (B) I joined Freelife International, and began drinking Go Chi juice (www.pbowen.freelife.com) because it has three scientific studies proving its effectiveness. (C) I stopped drinking caffeinated soda and began drinking a homemade blend of green (matcha) & darjeeling teas (if you want the recipe, e-mail me and I'll send it pamela.bowen@gmail.com), and (D) I bought a device called RESPERATE (www.resperate.com). I HAVE MY LIFE BACK!!! Don't think you have to live the way you are forever!

I took Toprol for 4 years. I gained 50+ pounds, had the worst dreams ever. They were so real, I would get out of the bed and put on my glasses to make sure I was seeing what I thought. Sometimes I would see actual performances. If I wake up and see a light, any light, even on the alarm clock, some figure would appear. I and my family thought I had lost my mind. I sweated like a maniac for no reason, you would think that I had just ran a marathon. My body ached, legs would be so heavy, especially upon waking. Sometimes I had to lay in bed longer because my legs were achy and too heavy to get up. I had brain fog, couldn't concentrate and my night vision was almost zero. I never felt like doing anything, the only thing I wanted to do was sleep. I never got a good night sleep, sometime I didnt sleep at all.
Being on Toprol was HELL!!!!!!!!! I am off now and I feel like a different person.

50 yr old female ( gasps @ 5-0 still)

I've been on ToprolXL for some time now. I started with Tenormin and felt FINE! The doctor then decided it was not the 'right medicine' for me and changed me to a 'new and better medication' names TOPROL XL, He started me on 50mg a day. I had experienced rapid heart beat of at least 150 bpm up to 200! My heart had to be stopped in the ER to get it back to being a normal rhythm. At the time I was 39 yrs old :( SCARY! I had every test imagined. Heart tests, lung and leg scans. You name it, I had it done to me ( thankfully, to make sure it was nothing serious). Although I do consider a heart beating that high to be serious! I already have a anxiety disorder, I noticed that my panic attacks are worse now more than ever! I am very very lethargic. Just thinking about doing ANYTHING makes me tired. I even getting tired when I talk too much! My mouth is always excessively dry. I put on weight and even paid for a diet that consisted of 2 'shakes' and one meal per day. Followed it to the "T"! and nothing ?! I've recently read that ToprolXL can lead to all kinds of diseases. One of them being Lou Gehrig's (ASL) :( I am SO very upset that medication is prescribed supposedly to make a person feel better AND I don't think I've physically felt this depleted and depressed in years! I want medical answers and I need support and words of encouragement from everyone that has been on this drug , most especially those weaned off ot it and are on a better drug. Most of the people I notice taking TOPROL XL are taking it fro HBP or symptoms other then the one's I have. I am SO confused now :(

I've been on the generic of Toprol XL for a month and a half. I take 12.5 mg in the morning and 12.5 at night. I have gained 10lbs so far, I feel groggy, lightheaded, fuzzy, sleepy all the time no matter how much sleep I get. I get episodes where it feels like an elephant is sitting on my chest making it hard to get a good deap breath. I have a headache almost every day. I suffer from severe anxiety to the point that I don't like leaving my house. I worry about stupid things obsessively. I just feel crappy constantly. I was prescribed it due to a high heart rate, but I've never had high blood pressure. I have a dr's appt May 6 and I'm going to ask her to start weaning me off of it. If I would have known the side effects would be this bad I would have asked to be prescribed something else from the get go.

I have been taking Toprol-XL for a long time. I have recently been switched to the generic and it is not controlling my blood pressure as well and my heart is palpitating a lot. I think I had problems before with the brand name but this is far worse. Is there a possibility that this drug causes Fibromyalgia??? I've seen some posts about that and I was also diagnosed with it because of severe muscle pain. If anyone has noticed a trend please respond, I am desparate.

Weight gain,muscle pain/tiredness especially in the lower legs. Fatigue/lack of energy, moodiness. Also intestinal bloating/gas.

Getting adequate exercise is problematic given I can't get my heart rate into my target area, and the almost constant pain and dead feeling in my lower legs. It gets to the point that I have to stop walking and wait for the blood flow to reach my lower extremities. I am assuming this is a large contribting factor to my weight gain.

I have been taking 25mg generic for about a year. Have had increasing short-term memory loss and beginning to have episodes of slight tremors. I can't correlate this with anything else except starting this med - can these things happen on such a low dose?

I have been taking kelone for 20 yrs due to palpitations and a rapid HR the pappitations got worse over the last few months and I was panicky so I went to the dr and this is what happened!

I was put on metoprolol 25mg 2x's a day and it didn't work. I found myself in the hospital with a rapid HR and not feeling well. I had been on kerlone/betaxolol for more than 20 yrs and my NEW Dr was not familar with it so he swithched me. I went to fill the RX and was told by the PharmD that it had a very short half life compared to my old med. I asked the Dr. he said lets try it. Well like I said I was in the hospital within 2 days. I wanted to know what you all think about switching from generic to Toprol Xl and what should my does be? I was raised to 50mg metoprolol 2x's a day and it still doesn't seem to work. I know it is wearing off and I feel crappy! I am 38 with a hx of type 2 Diabetes which is controlled and I take Metformin 500 mg er. I also take Crestor 20 mg all other things are ok but I can't excercise or do any activity due to the feeling my heart is going to POUND out of my chest.
Any and all advice is welcomed since I am new to this med and dont't know if I go back to the palpitations I had with my old one or feel like crap with the new one.

I am so glad that I found this site. I was put on Toprol in January and Just recentky i have panic attacks, chest tightness,tingling and numbing sensations in hands and feet, and i am deperessed. I also have some difficulty breathing. My Dr. told me that I am depressed and these side effects are from depression and not the medication so she gave me Zoloft, which I am not taking. I am not crazy i know that my symptoms are from the meds. i am going to wean myself off and pray i can be "normal" again. This is the worst time of my life and I pray that I can do this.

Has anyone been diagnosed with ALS (Lou Gehrig's Disease) after taking Toprol? My mother was just diagnosed and we feel it could be due to the medication. She is/was also taking Zocor.

I just discovered this after 3 months of total misery, 7 different doctors, multiple tests, 1 hospitalization, 16 pound weight loss, almost lost my job, etc., etc., etc.. I want to know if this will have permanent effects on my body and heart and will I ever be the same again. I have been back on the brand TOPROL XL for 9 days now. Keep in mind I didn't know what was happening to me, I never thought twice about the switch to generic, it was cheaper and I also had a lot of stress going on in my life at the time.

My pharmacy switched my "Toprol XL 50 mg" to a Generic one called "Metoprolol Succinate ER 50 mg" (manufactured by Sandoz) in December 2007. I have been on some form of Beta Blockers for years due to PVC's, AVNRT, Bigeminy, Trigeminy and Couplets. NOT High Blood Pressure. In my case I get very symptomatic from the arrhythmias: very low blood pressure, chest pain, fatigue, blacking out. I've had EP studies and attempted ablations in the past, but they were unsuccessful. For the last 2 years I had been under control on this med. Within a week of starting the new generic, I was at my eye doctor because my left eye went from 20/20 to 20/60 and was so blurry that I felt like I had suntan lotion or something in it. The new symptoms just kept coming. Since Dec 07, I have been to a Neurologist, Neuro-Ophthalmologist, Endocrinologist, Gastrointerologist, Ear Nose and Throat Doctor, Cardiologist, and many more. The generic form caused my arrhythmias to come back with a vengeance, I got depression, I couldn't sleep, my chest hurt, my BP was like 85/45, I lost 16 pounds and couldn't eat. I was almost passing out, seeing stars, I had bigeminy/trigeminy day and night for days on end, I was crying for nothing, very moody, I was coughing and wheezing, I had tingling in my arms and hands, loud ringing in my ears, I couldn't concentrate let alone think. I had tons of blood work that the doctors said, "just didn't look right". Upper GI test discovered a hiatal hernia, MRI discovered brain lesions, I had a high red blood cell count (but not anemic), my ferritin was high, my blood sugar was high, I was tested for MS, Lupus, thyroid, everything under the sun and was borderline for these diseases! I thought I was going to die, I had never been depressed in my life and this was the worst. I was beginning to think I was a hypochondriac. But, it was all there on paper, all the tests showed something wrong, but they didn't know what.

I googled Toprol brand versus generic and found out that it wasn't just me, thousands of people have had these same reactions since they started making Generic Toprol. Please read up on it, everyone who writes their story can't be wrong (there is at least one from every state complaining of the same thing). I've been taking the old TOPROL XL BRAND for the last 9 days and my arrhythmias have completely stopped, I have an appetite again and the depression has lifted. I hope it didn't cause any permanent damage.

I know this is probably happening to people everywhere who don't have access to the internet or maybe don't get out much. If you ask the pharmacist, they will tell you that they are exactly the same and they are NOT. The generic may work perfectly for you, but it doesn't work for all. In trying to figure out why I was so symptomatic, the doctors in the hospital took me off the beta blocker completely....I could have had a stroke or heart attack. I started back up on the brand name when after I googled it and realized that you can't just "go off" Toprol. I just wish I would have discovered it about 3 months ago. They thought for sure I had either MS or Lupus and were trying to rule out all the mimics of these very serious diseases. I'm going back to my doctors and have them repeat all the blood tests, etc. to make sure everything is back to normal.

I'm trying to get the word out.

62 year old male. After one month of taking it, my doctor raised me from 50 mg Metoprolol to 100 mg. No side effects until the dosage was raised. Then immediately got a traveling toothache, going from one tooth to another, culminating in an extreme earache. Had many of the symptoms mentioned in this forum, including short term memory loss resulting in my first auto accident in 40 years--a parking lot collision which was my fault. My doctor refused to ascribe any side effects to the drug except headache ; but I was told by local pharmacists that doubling the dose was too drastic and that my symptoms were typical. Had some rebound after stopping on my own a week ago, but pretty much back to normal, and the side effects are gone. I've tried other BP meds and am convinced that modern medicine just doesn't do it. Am looking into natural alternatives.

Has anyone here ever heard of anemia being associated with Toprol? Since they increased the dosage of my husband's Toprol, he has developed anemia and they cannot find a cause but every time I ask about the possibility that it could be the meds causing it (he is on coumadin, too), no one will firmly say no - always a "could be" - so just wondering if anyone else has had this experience. Thanks!

I was put on Toprol XL 6.5 yrs ago. My heart rate had soared to 130+ and b.p. was elevated. So my family doctor put me on Toprol XL 100 mgs. From day one I felt exhausted. He told me that would soon clear up and not to worry, we needed to be more concerned with my heart rate and b.p. I listened and was a good patient. After a year of total exhaustion and having to quit my job I asked to be taken off Toprol. He said it was the only medication that would control my heart rate and b.p. together. He agreed to reduce it to 75 mgs. After a few months I went back and said it was still too much! My b.p. was better as was my heart rate so he lowered it to 50 mgs. Things got a little better at least I could get out of bed by 10:00! Fed up I lowered it to 25 mgs. and tracked my b.p. Finally I told my doctor and he said as long as my b.p.was better 25 mgs.was ok. By this time though I was having other symptoms, body aches, joint pain, mind fog. He attributed it to arthritis and put me on Vioxx. 2 pills later I stopped due to chest pains. The symptoms I had experienced over the past 2 yrs continued so I sought a new physician. Once again he said Toprol XL was the only medication I could take for tachycardia and high b.p. My b.p. was again elevated so my meds were increased to 50 mgs. he wanted to go 100mgs., I said NO!
In 2004 I was diagnosed with Fibromyalgia, the pain had become so bad now it was debilitating. I had all the full blown symptoms of Fibro, extreme exhaustion, body aches, joint pain, mind fog, depression etc etc. So I sought treatment for Fibromyalgia for 3 yrs. Not so successfully I might add.
I should note that I had none of these symptoms before Toprol XL.

During a recent Gynecology visit my b.p. was extremely high. I told her my story about Toprol. She said point blank, They are NOT listening to you. I think all the side effects you have been having are due to the Toprol XL.She sent me to a Cardiologist. God bless her!!
After many tests he immediately took me off Toprol. He put me on another medication instead. I am having withdrawal side effects from Toprol, shakiness, shortness of breath, heart rate acceleration and mind fogginess. But, anything is better than another day on Toprol. He told me what I was experiencing was normal withdrawing from Toprol. He also assured me there were many other alternatives to Toprol and if the new medication doesn't work there are other options.
I think Toprol XL is the next drug that should be banned!! I pray everyday my life will return to what it was before Toprol XL and that I will not have any lasting side effects from this horrible drug.

I was on toprol-xl for almost 8 years without many problems. i also take isosorbide mononitrate.A few months back I was switched to the generic version (metoprolol succinate er by sandoz) now i have many problems.First I have to say I am disabled with severe COPD. Although I do not feel depressed I have a lot of symptoms of depression. Remember I had no symptoms what so ever until switched by Walgreen's or HMO or Doctor to the generic version. Not sure what to do I have a doctor that does not truly listen,plus he did not want me on toprol xl to begin with. Even though it was good for me. Good luck people!

I am 57 years old, and never had HBP, I went to the cardiologist and told me I have 140/80 and prescribed Toprol XL 25mg. I bought the generic ones. Today is my second week and I did not know that my headaches (never had headaches before), electric chocks ringing ears , breathing problems, were a side effect of this pill until reading all these experiences of so many people. I am going to cut half the dosis and lower it, so I get out of this medicine. The doctor made an EKG and gave me Toprol because my left atrial was big due to untreated HBP. Is there any natural product, better than this killing medicine, please advice.

Depression, rise in blood sugars, nausea, stomache, complete loss of appetite, gray foamy stools and being cold all the time. New doctor wasn't happy with my taking Inderol since I have diabetes, but it has worked well for 20 years and I have fairly good control on the blood sugars. The side effects hit me out of the blue, having been on beta blockers as long as I have Between being cold (It was 70 degrees out today) and the depression I don't even want to get out of bed. I didn't expect this. Still have a few of the Inderol, will call the doc tomorrow and switch back.

There is an important point that everyone here is missing. I had been on Toprol XL for years, brand name. Recently, a generic version by Sandoz has been issued. It is the GENERIC metoprolol that is causing the side effects, the racing heart, etc. If you can get the doctor to write "no substitutions" on the prescription, and get the original Toprol, you will notice the difference. the problem is, health insurance wants to push the generic, so you will pay more. but it's worth it to feel better!

What started out as a simple visit to dentist became a nightmare. My BP was high l73/90...so I went to a doc to get something for the BP. I knew it had been creeping up. I should have been more vigilent and done my own research first. He prescribed l00 milligrams of the generic brand--metropolol. I questioned the dose, but he said it was safe, and I needed something to bring my blood pressure down right away.

By the third day I felt like I had a hangover when I woke up. I started feeling not quite right. Tiredness, depression, and headache. My BP got higher. On the 5th day my heart started racing, with a pulse in the l30's. I spent 6 hours in the ER. My pulse was in the 60's, but BP 210/110. They injected me with 5 mg of the stuff, and also gave me clonopine. My EKG had been normal at the doc visit. In the ER it showed abnormal with sinus tachycardia and First Degree AV nodal block. It returned to normal, and by BP dropped to 150/80 with the clonopine. My glucose was also high at 300. I could feel an immediate relief with the clonopine. Heart enzymes normal. ER doc denied that the Topol caused the racing heart. He said that's not a side effect..perhaps there was an underlying cause. He did say the episode could have been triggered by low oxygen to the heart. I think they all stick together----he's not going to say the first doc was an idiot.

They wanted to transfer me to the "big" hospital for cardiac workup. I refused, since I had an appt.with a cardiologist in a couple days, and the doc that prescribed his awful med. I didn't think my insurance company should fork out $50,000 for an adverse effect from a drug.

I had been doing heavy exercise the morning of the racing heart...it was after I sat down I noticed the increase in pulse rate. NO ONE gave me any warnings..not the doc, or the pharmacist. Both said this was a safe drug.

I cut the dosage in l/2 for two days, until I saw the cardiologist. He said ok to stay on the clonopine for now, and a diuretic. I feel much better, and BP has dropped to the l40's over 80 something...pulse near 80. I am going to do a stress test. Based on a heart scan, 3 arteries have 0 plaque, and two mild.

I read that this drug is not recommended as first choice for BP. In the UK they're weaning people off of it because it causes diabetes, and there's other better drugs out there. I did not wait to "ask my doctor" to take me off of it. I told him I am not taking it....I don't know how much longer he will be my doc. I don't think he should have started at l00 milligrams to begin with...and should have started out slowly at the least.

Caveat emptor (buyer beware) when it comes to this med...and do your homework, and don't be afraid to fire your doctor!

I think it cause shakes and trembling for me,I started it in the end of august on toprol generic December I started shaking. and trembling.I have had thyroid checked ,brain scan plenty of blood work every thing checked out..

I just took my first pill of Toprol XL. Looks like I'm going to be in a world of hurt. I went running in prep for the police academy and after that my resting heart rate was 113 - 126. Did an ekg and it said my right atria was enlarged. Doctor gave me the Toprol but now I don't know if I really want since I'm already suicidal. If I don't respond in a week you'll all know I'm six feet under. Ha

I was given Metoprolol, a generic for Toprol-XL several months ago, for high blood pressure. It was prescribed after I was determined to be allergic to Lisinopril. ( It caused a cough that lasted 3 months; I sounded like a TB patient.) Anyway, I have been taking Effexor for years, for anxiety attacks. Now that I take Metoprolol along with the Effexor, I am so tired and drained all the time, that I am contemplating quiting work. I go to the grocery, come home and lie down. I can't seem to have energy to breath correctly. My Dr. won't believe that this has anything to do with meds. I have now developed blood and mucous in my stools, diarrhea, and very urgent BMs. This all started after taking these two meds in combination for about 4 months.

I thought I had already posted, but it isn't showing up. I am a 61 yr. old female who suddenly developed high bp in Dec. (sometimes 195/90) and had never had high bp. They tried a couple of different meds before lopressor (toprol?) and Norvasc worked. My bp is normal for me now, but after about 2 weeks I started getting numbness, tingling, a cold clamminess in one spot on my left leg. The numbness started gradually, and would change from a hand to a foot, but would go away. Eventually, it started being basically all over every day. I took a Xanax one day just because it was driving me crazy,and the numbness went away, so my doctor felt it had to be anxiety or the Zanaax wouldn't help. I had read that this could be a side effect of this med, so I talked to my doctor about it and he said to go off of it and see. He said it should be out of my system in about 3 days. Three days did not make a difference, so I thought it was anxiety. I started taking 1/2 Xanax in the morning and 1/2 at noon, and by noon the numbness and tingling would be starting again.

Now, I think it is the meds. I am trying to find an herbal alternative, but there are so many listed that I don't know which would really work and I can't find a doctor in this area that specializes in herbs. The Xanax is starting not to work as well as it did. Today, I took 1/2 of the bp medicine and felt better than in a long time, but it could be in my imagination.

HI, I was prescribed IC Metoprolol succ er 25 mg. same as Toprol xl. I feel tried, I am a fitness instructor and teach 13 classes a week. 8 aerobic and 5 weight training classes. I continue to gain weight. With this being a blocker, I have just come to find out this med wont let you heart rate go up when you exercise so you muscles can get oxygen and burn fat. The lack of oxygen makes you (us) more tried less motivated to workout or anything for that matter. It has effected me in this matter. I am calling my doctor to change my meds. this website was great. I new It had to be my meds, you don't workout this way and still gain weight!!!!!!!! I have always been very fit and muscular, something i took pride in. now I"m looking flabby. It"s really hard for me. Hard to motivate people when you don"t look like things I share with people all the time. hang in there the weight will come off just be consistent, when I continue to gain weight.

Have been taking Toprol XL since about June 2007. About three weeks ago suddenly developed insomnia. Went to my Doctor this past Thursday and told him about insomnia problem and asked if it could be connected to Toprol XL. He said he was unaware of insomnia problems with Toprol but that I should cut dosage in half from 100 mg to 50 mg per day as I had not had any problems at 50 mg per day. My blood pressure has also shot up this past three to four day after being low at the start of the week.

My doctor prescribed Ambien for the insomnia problem Slept okay the first night obn ambien but did not sleep well last night.

I just want to get back to normal. So, I am going to stay on top of doctor to get over the terrible insomnia problem.