Lisinopril and prednisone

Oh My Gosh - as I sit here with abdominal cramps typing my experience - I can see the light at the end of the tunnel. I started taking Lisinopril in late April 2008. On May 2 I had severe abdominal cramps and massive vomiting for 8 hours. Finally got myself to ER after I sent my family on to our vacation (I joined 2 days later). The ER attributed it to food poisoning. Lo and behold, I had another "attack" on May 9th. Back to ER I went (my husband witnessed my attack and insisted I go). They took X-rays and MRI - found intestinal inflammation but didn't know why. My internest send me to gastro dr. Third attack hit on June 5th and gastro doctor sent me to major hospital ER. They, too, did MRI & blood work. Looked at gall bladder, pancreas, stomach, intestines, etc. They found intestinal inflammation. Gastro Dr. took more blood and did more test (CT, MRI, Colonoscopy, Endoscopy). He couldn't find anything so he sent me to rheumatologist. She did add'l blood work and genetic testing. She though I had an auto-immune disorder - like Mediterranean Familial Fever! Please...! But all her tests came back negative. She too had no answers, only treatment for symptoms - Colchicine and Prednisone. Yuk. After having my 8th debilitating attack yesterday (since May), I've had enough. I went to the Web and found this wonderful site - along with some others with helpful info. I don't have confirmation that the lisinopril is causing this - but it sure sounds like it. I am a 49 yr old female and I've had no "life changing" events in my life (except for this nastiness) and have been on no other meds. I find it interesting that out of all the doctors I've seen - and all knew of the lisinopril - that none suspected this as a side effect.

September 25,2008 I was told to increase my dosage of Lisinopril from 10 mg to 20 mg and suddenly awoke on October 2, 2008 with a extremely swollen top lip, the degree was enough to get me into the ER room where I was issued Prednisone and Hydroxyzine with Famotidine which I had to take over the course of a few days to a week.

I was on Lisiniprol for 91 days as an ACE inhibitor for diabetes and kidney protection. All was find except for a constant feeling of burning blood all the time. It was tolerable though.

But on day 91 I developed hives. 14 days after that I was broken out from scalp to sole of my feet -- feeling miserable and no relief in site.

Dr. told me that I was allergic to something and to take benadryl. 3 doctors later I was told that I had hives and had to learn to live with it. He increased my benadryl.

I took myself off all my meds except insulin -- not knowing what was going on. I researched and discovered the this drug should NOT have been given to me because I also have SJOGRENS (an autoimmune disease akin to Lupus).

The hives got worse, my benadryl was increased by the drs. Finally I passed out due to benadryl toxicisity (overdosed) and they put me on prednisone.

To this day -- 6 months later -- I still have hive outbreaks that are miserable. I have missed a day from work every 7-10 days. The prednisone helps, but as a diabetic it sends y blood sugars through the roof. My rheumo has put me on doxepin (an antidepressant) because it has an antihystamine property that seems to be helping.

It is also useful for the rheumotoid arthritis that comes from Sjogrens and such. I am sleepy a lot -- but that could be from the doxepin.

I will never take Lisiniprol or any other ACE inhibitor. I am suffering and the worse part of it: the doctors and medical profession don't care and simply tell me to learn to live with it.

I have been io Lisinopril for several months, and the only side effect I can say is a VERY ANNOYING rash on the inside of my upper thighs. It comes and goes and gets worse with warmth, like a heat rash. I also have now developed a rash on my butt that is looks to me like shingles. Very itchy, to the point of bleeding from scratching. I treated with diaper rash ointment and triple antibiotic ointment to not much improvement. Reently tried a jock itch ointment which seems to be working. Also took myself off Lisinopril 2 days ago, and things are getting better, but very slowly........

Was previously on Micardis HCT; dr. switched to generic Lisinopril HCTZ 12.5 in 11/07 when I went on Medicare & was concerned about cost of Micardis. Since that time I've put on 10 lbs. and had increased pain/muscle fatigue and general lethargy. Unusual, as I've exercised 4-5 days per wk. (incl. aerobics/strength trng/flexibility.) for 20+ yrs. Also, frequently, have problems swallowing pills due to feeling of obstruction in esaphogus tube. In July '08 I awakened to slight numbness/tingling in lips and my lips then proceeded to the swell to the point of pain and my lips (in profile) protruded further than my nose. I received steroid injection and prescription for steroid pack. Diagnosis was possible allergic reaction to new cosmetic product. Today (9/3/08) I woke up with the same symptoms and again had to go to the dr.for a steroid injection & meds. Diagnosis this time (different dr.) was possible side effects of "blood pressure meds." Has anyone else experienced edema of the lips, wt. gain, and problems swallowing?

My husband started on Lisinopril - 6/11/08. He also takes Coreg generic. He also takes Crestor. However, before taking Lisinopril, he had a persistent cough dating back to March. He was placed in prednisone for five days - 6/14/08. He has had chest pain, numbing of different sections of his legs, arm numbness. But, today, he threatened to attack me with a remote control and wished a tv to fall on my head.
This is psychotic behavior. Has anyone else experienced violent eposides and incoherant moments?

I am a 56 year old woman and my doctor started me on 10 mg Lisinopril in March. Within 24 hours of starting it I developed a very annoying cough. At my next doctors visit she told me my bp was not down enough and wanted to increase the dosage. When I asked her if the cough could be from the Lisinopril she gave me some samples of Benecar HCT. The only problem I had with that was muscle weakness and some palpitations that went away after a few days. When I got the prescription filled I found that my insurance didn't cover it and it was quite expensive so I called my doctor back and she wanted me to try the Lisinopril again at 20mg and see what happened. That very same night the cough came back with a vengeance, along with dizziness. I decided to try to tough it out but after ten days now the cough is so bad it's unbearable. It keeps me up at night and I cough till I gag and cry. On several occasions I have coughed until I vomited. I couldn't take it any more and stopped taking it two days ago. I called my doctor today and she told me to stop taking it and now we're going to try Norvasc.

I've been having ringing in my ears (tinnitus) which started at about the same time I started taking Lisinopril. Has anyone else experienced this side effect?

I have been on Lisinopril-HCTZ 20/25 for about 5 weeks now and I have noticed a little dry cough recently and a constant runny nose. Since 3-15-08 I notice that my left ear has been losing some hearing and today the 18 of march it feels like I have something jammed in there and everything is severly muffled.I was just on Lisinopril at first and on 3-11-08 the Dr put me on Lisinopril-HTCZ 20/25 and this started 4 days after I started the drug I have not taken it today and don't plan on it after I I have read what I have just read. I am going back to see my Dr. this after noon.