Ethezyme and ulcer

My 92 year old mother-in-law had been using this product with her home health agency. She always experienced burning, drawing sensation and pain to the affected areas with her leg ulcers. She continually has alot of drainage and requires daily drsg changes. She has congestive heart failure and diabetes. A couple of wks ago, she was hospitalized with a bleeding vessel near one of her open wounds. She is on blood thinner medication. She had been using this product for about 3 months. Is there any correlation with her side effects which never went away and causing bleeding at ulcer sites. She has stopped the medication and returned to using silvadene. Would apprepreciate any feedback. Thankyou.