Lotrel Information
What's inside Lotrel
Lotrel Active Ingredients: amlodipine besylate, benazepril hydrochloride, details.| Lotrel Dosages & Strengths | ||||
|---|---|---|---|---|
| Strength | Format | Route | Strength | Class |
| Lotrel 5 mg-20 mg | capsule | oral | 1.0 each | OTC |
| Lotrel 5 mg-10 mg | capsule | oral | 1.0 each | OTC |
| Lotrel 2.5 mg-10 mg | capsule | oral | 1.0 each | OTC |
| Lotrel 5 mg-40 mg | capsule | oral | 1.0 each | OTC |
| Lotrel 10 mg-20 mg | capsule | oral | 1.0 each | OTC |
Recent Lotrel Side Effects
Posted by levibedwell3 10 days ago
I have swelling in my feet and ankles from taking Lotrel. It lowers my BP but now I retain fluid which makes me tired and irr...
Posted by derrickmoses123 14 days ago
i have taken lotrel 10-40 for 2 months and dry cough wake up at night 2-4 times feel tired all the time work 12 hours no ene...
Posted by dukat2 about 1 month ago
I started taking Lotrel in January and was thrilled because my bp was down from 165/97 to 100/70. Atenolol caused extreme fa...
Lotrel in the News
Teva Fourth-Quarter Profit Jumps on Protonix Copies (Update3) - Bloomberg
The drugmaker used this ``at risk'' strategy when it released Protonix in December and a version of Novartis AG's Lotrel heart medicine in May. ...
Tue Feb 12 05:52:37 -0500 2008
Market Spotlight: Generic Drugs - CNNMoney.com
A similar discount currently exists for Lotrel, a blood pressure drug made by Novartis (NYSE:NVS) , for which Teva enjoys market exclusivity with a generic. ...
Wed Feb 20 11:36:37 -0500 2008
Medco profit slips, but tops forecasts - The Star-Ledger - NJ.com
Generic versions of the in somnia treatment Ambien and the blood pressure drug Lotrel added $14.7 billion to revenue during all of 2007, the company said. ...
Wed Feb 20 09:02:31 -0500 2008
Lotrel Chemical Information
amlodipine besylate - The besylate salt of amlodipine, a synthetic, dihydropyridine, calcium channel blocker with antihypertensive and antianginal effects. Amlodipine inhibits the influx of extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells, thereby preventing vascular and myocardial contraction. This results in a dilatation of the main coronary and systemic arteries,decreases myocardial contractility, increases blood flow and oxygen delivery to the myocardial tissue and decreases total peripheral resistance. This agent may also modulate multi-drug response (MDR) activity through inhibition of the p-glycoprotein efflux pump.
benazepril hydrochloride - Thy hydrochloride salt of a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, benazepril hydrochloride is metabolized to its active form benazeprilat. Benazeprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Benazepril hydrochloride also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.
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