Diovan HCT Information

What's inside Diovan HCT

Recent Diovan HCT Side Effects

Posted by shorty09 19 days ago
I have been taken diovan now for about 4 months and I have no complaints. on last week my doctor switch me to lisinop/hctz bu...

Posted by sruliros 5 months ago
For a year or so I took a HALF of a Diovan 320/HCT25 tablet twice a day. It worked just fine. It controlled my blood pleasu...

Posted by angelo2555 about 1 year ago
I have been on Diovan for about three months now, and it has lowered my blood pressure. Unfortunately, I am experiencing a si...

Diovan HCT in the News

FDA Approves Novartis Blood-Pressure Treatment - Wall Street Journal
Novartis hopes that it will eventually become a multibillion dollar product, and analysts expect it to replace Diovan -- the company's current top-seller ...
Mon Jan 21 14:14:27 -0500 2008

Sepracor Announces Senior Management Appointments as Part of ... - PR-Inside.com (Pressemitteilung)
Diovan, Diovan/HCT, Lotrel, Zelnorm, Tekturna, Famvir, Miacalcin, and Exforge are registered trademarks of Novartis AG Corporation or its affiliate. ...
Mon Oct 15 04:10:38 -0400 2007

· Arteries stiffen naturally with increasing age, but this is ... - PharmaLive.com (press release)
The study compared the effect of a Diovan-based treatment (Diovan-HCT) with that of amlodipine on aortic pulse wave velocity (Ao-PWV – a measure of arterial ...
Thu Sep 20 13:33:02 -0400 2007

Diovan HCT Chemical Information

hydrochlorothiazide - The hydrogenated derivative of chlorothiazide, a thiazide diuretic with antihypertensive and anti-urolithic effects. This agent binds to the electroneutral Na-K-Cl cotransporter (NKCC) and thereby impairs Na+, K+ and Cl- reabsorption on the luminal membrane of the early segment in the distal convoluted tubule in the kidney. This leads to an increase in urinary excretion of sodium, chloride, potassium, bicarbonate and water subsequently reducing plasma and extracellular fluid volume leading to a reduction in blood pressure. Hydrochlorothiazide also decreases urinary calcium and uric acid excretion by direct action on the distal tubule.

valsartan - An orally active nonpeptide triazole-derived antagonist of angiotensin (AT) II with antihypertensive properties. Valsartan selectively and competitively blocks the binding of angiotensin II to the AT1 subtype receptor in vascular smooth muscle and the adrenal gland, preventing AT II-mediated vasoconstriction, aldosterone synthesis and secretion, and renal reabsorption of sodium, and resulting in vasodilation, increased excretion of sodium and water, a reduction in plasma volume, and a reduction in blood pressure.