Bactrim Pediatric Information

What's inside Bactrim Pediatric

Bactrim Pediatric in the News

A night in the life of KMC's ER - Bakersfield Californian (subscription)
Bateman gets some more Bactrim, which treats MRSA, and pain medicine. About an hour later, Sylvia Abrigo, who worries she’s miscarrying, is taken to a room ...
Fri Feb 29 20:43:23 -0500 2008

Drug-Resistant Staph Germ's Toll Is Higher Than Thought - Washington Post
The infections can often still be treated by lancing and draining sores and quickly administering other antibiotics, such as bactrim. ...
Wed Oct 17 03:37:02 -0400 2007

Bactrim Pediatric Chemical Information

sulfamethoxazole - A broad-spectrum, short-acting sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial property. Sulfamethoxazole competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death.

trimethoprim - A synthetic derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties. As a pyrimidine inhibitor of bacterial dihydrofolate reductase, trimethoprim binds tightly to the bacterial enzyme, blocking the production of tetrahydrofolic acid from dihydrofolic acid. The antibacterial activity of this agent is potentiated by sulfonamides. (NCI04)