Alprazolam ER Information

What's inside Alprazolam ER

Alprazolam ER in the News

Heath Ledger Post-Mortem: When Mixing Medicine Kills - Wall Street Journal
In 2005, nearly 600000 people showed up at the ER because of side effects from nonmedical use of prescription drugs — and most of those people had taken ...
Thu Feb 07 08:50:32 -0500 2008

Accidental Overdose Killed Heath Ledger - Guardian Unlimited
... temazepam, alprazolam and doxylamine as causing the actor's death. There was no mention of alcohol or illegal drugs.er she arrived for an appointment at ...
Wed Feb 06 20:34:28 -0500 2008

Alprazolam ER Chemical Information

alprazolam - A triazolobenzodiazepine agent with anxiolytic, sedative-hypnotic and anticonvulsant activities. Alprazolam binds to a specific site distinct from the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) binding site on the benzodiazepine-GABA-A-chloride ionophore receptor complex located in the limbic, thalamic and hypothalamic regions of the central nervous system (CNS). This binding causes an allosteric modification of the receptor and enhances the affinity of GABA to the receptor leading to an increase in the frequency of chloride-channel opening events. This leads to an increase in chloride ion conductance, neuronal hyperpolarization, inhibition of the action potential and leads to a decrease in neuronal excitability.