I took Metformin two years ago when i was trying to get pregnant. I have PSOS and i think the meds helped. I have an 11 month old. The Dr. put me back on Metformin 1000mg twice a day to help me lose the baby weight. So far i have not lost any weight but i don't take the meds regularly either due to the severe diarrhea. I normally take 1 pill once a day instead of twice.