Memory impairment symptoms and conditions

THE P.ORANGI REPORT
VERY VERY VERY ANGRY.
THE FOLLOWING IS AN abbreviated EXTRACT FROM MED SAFE NEW ZEALAND.
A watching brief for health professionals from the New zealand goverment's web site called MEDSAFE. I assume our equivalant of the FDA.
The centre for Adverse reactions Monitoring (CARM) is receiveing an increasing number of reports of psychiatric reactions occurring with statins, fibrates and ...ezetimibe. ...... aggressive behavior, memory impairment mood cognitive sleep and perception disorders. In Australia 9 cases of depression 3 cases of depressed mood ....... with ezetimibe use ..... onset happened within 4 days in 7 of the cases.

This reminder goes on to STATIN REMINDER to PRESCRIBERS of myopathy rhabdomyolysis and interactions.

In my small town this last week alone I have personally met 4 statin sufferer's. The last one yesterday was a charming wonderful 79 yr male, who could not see or hear properly, was aggressive to his wife and having hallucinations so severe in his words "I was to f'n scared to go to bed at night and wanted to leave (sell) his house. He stopped his medication (Fiblap 200 mgs) and the hallucinations stopped his other problems are improving.

It is now very obvious to logical people that not just statins but most cholesterol lowering medicines cause an extremely unacceptable amount of cruel dangerous adverse events. It is also very clear and almost undisputable by the statistical and very definitely UNDER reported number of these adverse effects that unnecessarily interfering with the body's cholesterol is extremely dangerous to all of us.

I can right at this moment show 3 middle aged men who are a complete danger on the road - their memories are completely shagged, they are agitated, not remembering simple landmarks and they are driving.

We have pilots in the air on this stuff, I would rather my pilot was on cannabis than this this shocking stuff.

Mr and Mrs prescribe it is you that are NOT reading the instructions it is you that are criminally negligent when the presentations are given to you and you fail as the safe process of elimination to cease this medication to your patients.

We the younger middle age are accepting of evolution, the trial, error and mistakes made in the pathway to achievement. Their is no shame in error, error in develpoment aids development and the end result.

BUT Messer's prescribes your negligence in failing to report adverse events, failing to take notice of your own government's warnings and consequently destroying the quality of life of society's grandparent's golden years is shameful and criminal and you can expect little sympathy as this debacle is inevitably exposed.

My own case in brief over a 5 year period shut down my weeze pooze and manhood. Gave me excruciating pain in every joint muscle and spasming eyeballs. Rashes, itching,muscle spasms, tremors. Insanity stopping a car and smashing my walking stick over the roof with a lady inside, hearing voices and stalking the house with an axe, being sexually suggestive to elderly lady customer, abusing customers, wife mother and friends. Driving with no recollection of towns I'd been through. Leg muscle cramps that dropped me. Decrease eye sight and hearing, when swallowing the food going down the wrong pipe. Unable to speak coherently, crying, hugging people in a special needs manner, selling my cars (2) for fear of failure of a warrant of fitness. An unnecessary hip replacement, that had me on a crutch for 6 months and 18 months later still severely limping and unable to lie on the THR side (weaken muscle). I swallowed almost 3000 pills in a 6 month period. Terrifying hallucinations, sweats that soak the bed. Completely unable to think, unable to print my own name, unable to remember neighbors names etc etc etc. Burst out in a totally deranged fit of laughter in a solicitor's face in the swimming pool changing shed. Obscene language in places where I never in my life used before To scared to go to bed at night for hallucinations and my heart stopping. Unable to keep up with my 6 yr old mate on our push bikes Almost 12 months since ceasing statins I have All the same problems though substantially reduced, I still need oxycontin, predisone coq10 fish oil. I am embarrassed about going out because of what I have done and because I'm still scared about what will come out of my mouth. I still blackout and "whiteout" (I know what is around me but I can't speak) I still have micro hallucinations and loose touch with reality.

DRUG COMPANIES, you have bought us fantastic medicines thank you. We know with development there are inevitable failures so why not own up do not cover up. The oxycontin makers and their directors were fined in the millions for their misrepresentions and they weren't giving a "safe preventitve" drug to airline pilots that are now known to cause mental impairment.

CHILDREN of the elderly, check your parents overall health, memory agitation aches and pains etc since starting cholesterol lowering medicine. Check whatever and all symptoms they have suffered since starting cholesterol lowering medication. If you are suspicious respectfully ask your doctor if your parent as a process of elimination can cease the medication for a while. Two major hassles are 1) We are not aware these adverse effects are happening to us or we may blame another cause, old age etc 2) Like me there is no way I was prepared to stop my medication, even though i knew I was dying, until I got my "TRUSTED" doctor's ok. I would never interfere with my mums meds.

TO OUR DOCTORS in our society, dog people, school groups, all clubs, trades, lawyers and even sick p*****s all have access to a data base of events that interest them but you don't. In todays easy communication society with a computer on your desk your are unable to readily access current helpful information. Shame on you.

TO MY DOCTOR, Over 3 years I complained of severe upper leg muscle cramps that made me squeal and dropped me, I complained of excess tiredness, I complained of loss of muscle power, you witnessed me in a trance in your surgery, you witnessed me 6 months on a crutch after a THR, you witnessed me with notes in your surgery (memory), you witnessed me loose my ability to talk and humor properly. I caught you red handed on several occasions not reading lab results and letters from other health professionals, you witnessed, stood up behind your desk and took off my hunched ape like stance. You completely ignored at least 2 med safe warnings I asked you for an apology you held your bunched fist in my face in your surgery and told me I was an ungrateful c&*t and to get another doctor. I wrote to you in my deranged state offering you forgiveness and hoping for medical help, you ignored that letter. When I started "sobering up" 6 months later I called you and told you of my insanity whilst under the influence of statins. You told me to tell another doctor or a medical specialist. I told you I would publish these events - you told me to go ahead. Doctor . . . . . my wife and I did not only like and respect you, I had a very grateful "love" for you and your staff. When I asked you for an apology and wrote to you, had you been reasonable and a little sympathetic to my life threatening condition, I would have warmly embraced you, forgiven you and been grateful that others would be safe. When I phoned you several months later, had you have been humane, though difficult, I would have done my best by you and society. Doctor ..... you had 3 very sincere approaches that you declined. Well bud do I know of others or not? Audit all your patients for their safety now. You told me to publish, well Doctor . . . .you may now become internationally famous. Do you think I will put a complaint to the Health and Disability commissioner where they will on proof order an apology - I don't think so, you have had 3 genuine chances for an apology. Did you report my severe adverse event to CARM? Doctor . . . . . I do not think this is conduct "unbecoming" I think it may be crime.

I sincerely wish I had never become "responsible" for my health. Given this web site, the victims I personally know, my own tragic events with statins, I now firmly, sanely and sensibly believe that JIM BEAM BOURBON and ROLL YOUR OWN CIGGIES are far more deserving of a heart foundation tick than statins.

This medications web site has saved the quality of life and indeed the lives of many people. Please take the time on the contact us to send our friends at medications an email with 4 wordS only " THANK YOU ALL VERY MUCH"

Signed Mr P. O.

PS To the police and lawyers in NSW Australia where the tragedy of the fellow who chopped his wife and grandchildren took place, please check whether he was on this medicine. My heart goes out to him and his family

PPS I DO NOT UNDER CIRCUMSTANCES wish to be contacted by anyone, with the sole exception of any authority, whose sole purpose is to benefit mankind, over this matter only, I wish to rebuild 5 traumatic years of painful destruction quietly with my family.

PPPS Any pilots in any country please forward this site and medsafe nz to your medical examiners.

PPPPS Prescribers COQ10, ubiquinol not the cheaper ubiquone, oxycontin, prednisone, large quantities of fish oil, vit C, time and patience are the only things that have been of aid. After almost 2 years on oxycontin, I have no hankling for it, I have built a resistance to it and I am now trying miniscule amounts of cannibis (I am filthy angry that I have been put in this situation) to replace the oxycontin. The fish oil calmed my agitation, the coq10 reduced pain by about 20% increased energy by about 20% 3 x 100 mgs a day, The fish oil and coq10 together stopped all irregular heartbeats showing in my BP meter. The vitamin c 6 x 1000 mgs through the day within days put pressure back to the urine and aided bowel movements.

Five weeks after my daughter received 2nd dose of gardasil she began complaining of neck pain & stiffness. Fevers accompanied this for about a week. I found her early one morning seizing and foaming at the mouth. By the time we arrived at the er via ambulance she was in respiratory failure and had several seizures. She was intubated and continued seizing repeatedly for several days. She was placed in a medically induced coma for six weeks in hopes of "resetting" her brain to stop seizures, as there was no explanation as to why they started.After coming out of coma seizures continue and still do after one year. She has brain atrophy, gait abnormality, severe behavioral and emotional problems, memory impairment, ticks, numbness to limbs, impulsive uncontrollable erratic behavior, and of course uncontrolled seizures. After several months in hospital and numerous tests there is still no answer. She was perfectly healthy before this vaccine. She also received 3rd dose and was hospitalized again for increased seizure activity. She needs constant adult supervision at all times, falls when seizing, and is unable to carry out simple activities of daily living without reminders and supervision. She is almost fourteen and is living with the mentality of a 5 year old.She has no chance of ever leading a normal life.

The example that I am posting below is not the only patent for an aminoquinoline derivative that is proposed for the treatment of neuro-psychiatric disorders. Even though we are not comparing exact chemical structures, it is certainly worth considering how the quinolines relate to this receptor.

It is also worth considering why montelukast, a quinoline, seems to be causing some of the problems that this owners of this particular patent think that they can treat.

As I mentioned before, I have no answers. Regardless of how small Merck believes the population of Singulair patients who suffer neuro-psychiatric disorders is, I do not believe that any patient should be ignored. It also seems that many companies have studied this area in depth and more than one company knows a lot more than we know about why it is possible for these side effects to happen.

" The compounds of formula I have a good activity on the 5-HT.sub.5A receptor. Therefore, the invention further provides methods for the treatment of depression (which term includes bipolar depression, unipolar depression, single or recurrent major depressive episodes with or without psychotic features, catatonic features, melancholic features, atypical features or postpartum onset, seasonal affective disorders and dysthymia, depressive disorders resulting from a general medical condition including, but not limited to, myocardial infarction, diabetes, miscarriage or abortion), anxiety disorders, (which includes generalized anxiety and social anxiety disorder, panic disorders, agoraphobia, social phobia, obsessive compulsive disorders, post-traumatic stress disorders, psychotic disorders (which includes schizophrenia, schizoaffective disorders, bipolar disease, mania, psychotic depression, and other psychoses involving paranoia and delusions), pain (particularly neuropathic pain), memory disorders (including dementia, amnesic disorders and age-associated memory impairment), disorders of eating behaviors (including nervosa and bulimia nervosa), sexual dysfunction, sleep disorders (including disturbances of circadian rhythm, dyssomnia, insomnia, sleep apnea and narcolepsy), withdrawal from abuse of drugs (such as of cocaine, ethanol, nicotine, benzodiazepines, alcohol, caffeine, phencyclidine and phencyclidine-like compounds, opiates such as cannabis, heroin, morphine, sedative hypnotic, amphetamine or amphetamine-related drugs), motor disorders such as Parkinson's disease, dementia in Parkinson's disease, neuroleptic-induced Parkinsonism and tardive dyskinesias, as well as other psychiatric disorders and gastrointestinal disorders such as irritable bowel syndrome (WO 2004/096771). "

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I've been on Lipitor for 1 year and have all the side affects that you all are describing.
I've also developed an inflamed liver.
Any one else?
if I get more response, I'm seriously considering a lawsuit against the pharmacy company.

Tom

Heart attack 15 years ago, bypass 5 years ago. Have been taking 40 to 80 mg lipitor per day for about a year after being switched from zocor due to high triglicerides (400+), high LDL & diabetes. Also taking zetia & niacin since March. Results, over last 5 months fatigue and short term memory impairment have become debilitating, affecting home & work. For awhile I thought it was all in my mind.
Stopped lipitor about a week ago and have noticed less fatigue & way better short term memory.
Lesson: Pay attention to what your body is telling you.

50 mg./ weight gain (10 lbs.), short term memory impairment, decreased sex drive, but fewer migraines and anxiety symptoms, straining sensation in chest gone

Concerning the adverse side effects of Lipitor. I know many have had their lives devastated by muscle damage and memory impairment. One can't help but ask why. Why is this happening to so many people, yet Lipitor remains on the market.

Unfortunatley, I have the answer to that question. For the thousands of people reading this posting, lets all say it together now. IT'S ALL ABOUT MONEY! Good, lets say it one more time. IT'S ALL ABOUT MONEY! Congratulations. You have graduated. Your deploma will be sent in the mail.

I had a severe reaction on 20 mg of Gabitril. I have taken it for a year. On four occasions the worst, just a few days ago landed me in the ER and hospital. I had extreme vertigo, confusion, memory impairment and severe language problems. My breathing was labored at times, I was totally disoriented. Be careful if you take this. I would be curious if other people have experienced this. I was not on other medication.